Turkey Time! Sleep Time! Vitamin D and Tryptophan

December 02, 2025

Are you staring at the ceiling each night, unable to sleep as morning approaches? With the holiday season upon us—packed schedules, family gatherings, financial pressures, and endless to-do lists—it's no wonder so many of us are losing sleep. If counting sheep isn't making the cut anymore and holiday stress is preventing you from relaxing, your body might be sending you a message—and the answer could be simpler than you imagine. As chiropractors practicing chiropractic care, we know that wellness can go past the spine care to include nutrition and exercise and more. Your sleep quality impacts everything from your immune system to your back pain levels, which is why we're excited to share some very curious research about two nutrition-based sleep supporters: tryptophan and vitamin D3.

VITAMIN D3: YOUR SLEEP-WAKE CYCLE'S BEST FRIEND

Think vitamin D3 is just for strong bones? No quite! Recent research by Wu and colleagues reveals that vitamin D3 has a crucial role in regulating your body's stress response system—particularly your hypothalamic-pituitary-adrenal (HPA) axis. When sleep gets interrupted (think: holiday anxiety!), this system goes crazy, triggering inflammation and throwing your gut health off balance. (1)  Here's the curious part: the study found that vitamin D3 supplementation helps restore this delicate balance, supporting your body's natural sleep-wake rhythm while strengthening your immune system. It's like giving your internal clock a much-needed tune-up through the most stressful time of year!

TRYPTOPHAN: NATURE'S SLEEP SIGNAL

You've probably heard about tryptophan making you sleepy after Thanksgiving dinner, but this amino acid deserves way more credit. Wong and colleagues found that tryptophan, especially when blended with prebiotics, works via a fascinating pathway—your gut. (2) By reducing inflammation and boosting healthy gut bacteria, tryptophan helps your body make the right sleep-promoting chemicals at the right time. Your gut literally communicates with your brain about when to sleep, and tryptophan helps ensure they're speaking the same language—even when holiday stress is shouting over it.

THE BOTTOM LINE

Sleeping better doesn't demand complicated medications. Supporting your body with vitamin D3 for hormonal balance and tryptophan for gut-brain communication can make all the difference this holiday season.

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